A Note on Photography and the Simulacral by Rosalind Krauss

By Rosalind Krauss

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1998). Inhibitors of mammalian DNA topoisomerase II are not necessarily effective inhibitors of these bacterial enzymes and, as a result, may not be detected in microbial assays for mutagenic and clastogenic effects. A number of drugs target DNA topoisomerase I, a different enzyme, which introduces transient single-stranded nicks into DNA. These drugs are not considered in this volume. C. R. (1998) Mutagenic properties of topoisomerase-targeted drugs. Biochim. biophys. R. & Sultan, C. (1985) Proposed revised criteria for the classification of acute myeloid leukemia, a report of the French–American–British cooperative group.

The types associated with exposure to DNA topoisomerase II inhibitors are typically acute myelomonocytic (FAB subtype M4) and monoblastic (FAB subtype M5a) leukaemias, but other AML subtypes, myelodysplastic syndrome, acute lymphoblastic leukaemia and chronic myeloid leukaemia have also been described. Table 1. , 1996). Leukaemia preceded by myelodysplastic syndrome was recognized as a risk associated with anti-cancer chemotherapy with alkylating agents long before the association of DNA topoisomerase II inhibitors with leukaemias was described.

M. Squirrell & W. Thain (1978) Vol. 3. Analysis of Polycyclic Aromatic Hydrocarbons in Environmental Samples (IARC Scientific Publications No. 29). Edited by M. Castegnaro, P. Bogovski, H. A. Walker (1979) Vol. 4. Some Aromatic Amines and Azo Dyes in the General and Industrial Environment (IARC Scientific Publications No. 40). Edited by L. Fishbein, M. K. O’Neill & H. Bartsch (1981) Vol. 5. Some Mycotoxins (IARC Scientific Publications No. 44). Edited by L. Stoloff, M. Castegnaro, P. K. O’Neill & H.

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