Acute Ischemic Stroke: An Evidence-based Approach by David M. Greer

By David M. Greer

This concentrated booklet bargains truly and concisely with the rules of administration of sufferers with acute ischemic stroke (AIS). It emphasizes the printed and verifiable facts in aid of those rules, and highlights the parts of restricted proof. most sensible facts is supplied for the present common remedy of acute ischemic stroke, together with intravenous chemical thrombolysis, intra-arterial methods, blood strain administration, and anti-thrombotic remedy. extra sleek recommendations also are defined, similar to using mechanical units to evacuate a thrombus, prompted high blood pressure, hyper-oxygenation (hyperoxia), and neuroprotective or neuroregeneration brokers. Hallmark good points comprise:

  • Focused on acute ischemic stroke, the main quickly transforming into region of stroke management
  • Evidence established: offers top proof for treatment
  • Clearly discusses parts and issues the place most sensible proof has now not but been established
  • Lays out treatment options and protocols in instruction manual type for ease of use and reference, even in emergency situations
  • Includes most modern and state of the art thoughts and kit for facing AIS

Acute Ischemic Stroke: An Evidence-based Approach is an integral reference paintings for neurologists, neurocritical care medics, intensivists, hospitalists, emergency room physicians, neurology citizens and fellows. it's also a beneficial source for scientific scholars, health practitioner assistants, and nurse practitioners in health facility and neurocritical care facilities.

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Neuroradiology 2000;42:722–727. 25. Fiebach JB, Schellinger PD, Jansen O, Meyer M, Wilde P, Bender J, Schramm P, Juttler E, Oehler J, Hartmann M, Hahnel S, Knauth M, Hacke W, Sartor K. CT and diffusionweighted MR imaging in randomized order: diffusion- weighted imaging results in higher accuracy and lower interrater variability in the diagnosis of hyperacute ischemic stroke. Stroke 2002;33:2206–2210. 26. Mullins ME, Schaefer PW, Sorensen AG, Halpern EF, Ay H, He J, Koroshetz WJ, Gonzalez RG. CT and conventional and diffusion-weighted MR imaging in acute stroke: study in 691 patients at presentation to the emergency department.

Intracranial vascular stenosis and occlusion: diagnostic accuracy of three-dimensional, Fourier transform, time-of-flight MR angiography. Radiology 1994;193:187–193. REFERENCES 33 63. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY. Dynamic CT measurement of cerebral blood flow: a validation study. Am J Neuroradiol 1999;20:63–73. 64. Nabavi DG, Cenic A, Dool J, Smith RM, Espinosa F, Craen RA, Gelb AW, Lee TY. Quantitative assessment of cerebral hemodynamics using CT: stability, accuracy, and precision studies in dogs.

3. Combined analysis of parts I and II of the NINDS study confirmed the effect of IV rt-PA on favorable outcome at 3 months. There was no difference in mortality (17% for rt-PA group vs. 21% for placebo, p ¼ 0:30). There was, however, an increase in symptomatic intracerebral hemorrhage (sICH) in the rt-PA-treated group (6% vs. 6% in the placebo group, p < 0:0001) during the first 36 hours poststroke. Among those with sICH, the 3-month mortality rate was 61%. Therefore, the improvement in 3-month stroke outcomes in the rt-PA group and the overall lack of increased mortality compared to placebo occurred despite the excess mortality from sICH in the rt-PA group.

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