By Maurice Victor, Allan H. Ropper
You recognize it because the masterwork in its field...and now, you could personal the latest, most modern model of this vintage textual content: Adams and Victor's ideas OF NEUROLOGY, seventh variation. This striking quantity now contains the most recent findings within the growing to be parts of neurology whilst it keeps its authority, entire scope, and well known, easy-use layout.
ways neurologic sickness simply as you'll strategy the sufferer!
Adams and Victor's ideas OF NEUROLOGY, seventh version, starts with a close exposition of the indications and indicators of disordered anxious functionality, simply as you are going to start with signs as offered through a sufferer. The textual content logically proceeds to syndromes after which to an outline of the entire major different types and kinds of illness that specific themselves by means of each one syndrome.
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Bilateral infarction of the medullary pyramids from occlusion of the vertebral arteries or their anterior spinal branches is a very rare cause of quadriplegia. Repeated cerebrovascular accidents may lead to bilateral hemiplegia, usually accompanied by pseudobulbar palsy. In infants and young children, aside from developmental abnormalities and anoxia of birth, certain metabolic cerebral diseases (metachromatic and other forms of leukoencephalopathy, lipid storage disease) may be responsible for a quadriparesis or quadriplegia, but always with severe psychomotor retardation.
These subjects are discussed in the section on muscle disease. CHAPTER REFERENCES AIDS TO THE EXAMINATION OF THE PERIPHERAL NERVOUS SYSTEM. London, Ballière Tindall/Saunders, 1986. ALEXANDER GE, DELONG MR: Mechanisms of the initiation and control of movement, in Asbury AK, McKhann GM, McDonald WI (eds): Diseases of the Nervous System: Clinical Neurobiology, 2nd ed. Philadelphia, Saunders, 1992, chap 21, pp 285–308. ASANUMA H: Cerebral cortical control of movement. Physiologist 16:143, 1973. ASANUMA H: The pyramidal tract, in Brooks VB (ed): Handbook of Physiology.
The areas richest in dopamine are the substantia nigra, where it is synthesized in the nerve cell bodies of the pars compacta, and the termination of these fibers in the striatum. In the most simplified models, stimulation of the dopaminergic neurons of the substantia nigra induces a specific response in the striatum—namely, an inhibitory effect on the already low firing rate of neostriatal neurons. However, the effects of dopamine have proved more difficult to unravel, in large part because there are now four known types of postsynaptic receptors (D 1 to D4), each with its particular anatomic distribution and pharmacologic action.