Case Studies in Sleep Neurology: Common and Uncommon by Antonio Culebras

By Antonio Culebras

Sleep issues are more and more famous as a tremendous scientific challenge, with major morbidity and huge financial significance. This compendium of case reports provides a various variety of occasions which problem the problem-solving talents of all these drawn to sleep issues, protecting either universal and strange instances. every one case starts off with a medical heritage, through exam findings and specific investigations and culminating in analysis, therapy and administration, with dialogue of differential analysis the place applicable. Focusing recognition at the significant different types of sleep drugs, together with insomnia, hypersomnias, sleep-breathing issues, parasomnias, stream problems, circadian dysrhythmias and the neurology of sleep, this medical consultant promotes integrative pondering and diagnostic ability. historic and evaluate citations, illustrations and concise real-life tales stimulate reminiscence and facilitate studying. Written and edited through a world cadre of sleep execs, this e-book will tell and problem demonstrated experts and supply a stimulating educating device for these in education.

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Cardiac diseases were excluded by clinical examination and appropriate investigations. Clinical respiratory examination, spirometry, blood gas analysis, and chest and neck CT were normal. Involuntary deep inspiratory sighs (gasps) were occasionally observed while the patient was awake and were not related to a specific effort. Special studies The neurologist ordered full-night video-polysomnography (PSG) including electroencephalogram (C3-A2, O2-A1), right and left electro-oculogram, surface EMG of the mylohyoideus, intercostalis, right and left tibialis anterior and extensor carpi radialis muscles, tracheal microphone, oro-nasal airflow, thoracic and abdominal respirograms (strain gauge), ECG, arterial blood pressure (Finapres) and oxyhemoglobin saturation by means of ear oxymeter.

1). Diagnosis The diagnosis was narcolepsy with cataplexy. Follow-up CSF hypocretin analysis was not performed in light of the diagnostic certainty, given her history of EDS with cataplexy, hypnopompic hallucinations and the MSLT results. After the initial sleep clinic consultation, she was started on modafinil 200mg, with significant improvement of her daytime sleepiness and school performance. 1 Thirty-second epoch showing sleep-onset REM in the first epoch of nap 3 of the MSLT recording. Note the vigorous eye movements in leads LOC-A2 and ROC-A1 and the absence of muscle tone in the chin EMG.

The episodes lasted less than a minute and had caused anxiety. On specific questioning, Mr. X. acknowledged falling asleep while driving, only to be awakened by the noise caused when riding over the rumble-strips on the side of the road. He would take naps almost daily that were refreshing and always associated with vivid dreams.

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