Huntington Disease - A Medical Dictionary, Bibliography, and by Icon Health Publications

By Icon Health Publications

It is a 3-in-1 reference ebook. It supplies an entire clinical dictionary protecting countless numbers of phrases and expressions on the subject of Huntington illness. It additionally provides broad lists of bibliographic citations. eventually, it offers info to clients on the way to replace their wisdom utilizing a number of net assets. The booklet is designed for physicians, clinical scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to get to grips with study devoted to Huntington sickness. in the event that your time is effective, this publication is for you. First, you won't waste time looking the net whereas lacking loads of appropriate details. moment, the e-book additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing 1000s of web content.

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Extra info for Huntington Disease - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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Although such animals now exist, the exact mechanisms by which mutant genes cause neurologic disease remains unclear. Unless the etiologic mechanisms underlying the neurodegenerative diseases are clearly identified, rational therapeutic interventions will be impossible. The neurotransmitter glutamate has been implicated as a causative factor in the etiology of neurodegenerative disorders. Specifically, one class of glutamate receptors, the metabotropic glutamate receptors (mGluRs), may be specifically abnormal in many of the neurodegenerative disorders.

We further extend the studies to movements where dynamics are not dependent only on arm kinematics, but also on other cues: external cues where dynamics are linked to an arbitrary spatial or color cue, internal cues where dynamics depends on position of a movement with in a sequence. We compare how damage to the brain in Huntington's disease vs. cerebellar disease affects this learning. However, motor memories are not static. Their functional properties change within hours after a task is learned.

Many of the measures of motor performance and functional status commonly used in clinical trials and rehabilitation suffer from subjectivity and lack of scientific validation. The first goal of the proposed study is to characterize and quantify the motor deficit in these diseases using methods previously developed in the study of arm movements in normal subjects. In particular, we will emphasize the importance of examining motor learning abnormalities because we hypothesize that these will give a direct measure of a patient's capacity to compensate or recover from neurological disease.

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