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Red-green changes are experienced by our brains thanks to comparisons between our long- and medium-wavelength sensitive cones, L and M, respectively: greater activity in L cones relative to M cones leads to redder perceptions; greater activity in M cones relative to L cones leads to greener perceptions. The blue-yellow changes are experienced by our brains thanks to comparisons between our short-wavelength sensitive cones, S, and the average of the other two: higher responses from S cones relative to the other two lead to bluer perceptions; lower responses to S cones relative to the other two lead to yellower perceptions.
Whether skin is red or green depends on how much oxygen is in the blood underneath it. There is no simple way to raise and lower the oxygenation level of the blood beneath your skin, but one way to observe the red-green changes is by comparing your skin’s color in the two cases we already discussed: over veins and when using a tourniquet. In each case, there is more blood than normal, but the 22 the vision revolution color of the former is greenish-blue, and the latter is reddish-blue. The difference is that the former involves less oxygenated blood, and the latter involves more oxygenated blood.
One can see that M and L have very similar sensitivities (maximum sensitivities are about 535nm and 562nm, respectively). Also shown is a model spectrum from human skin. A characteristic feature of skin is the “W” shape formed at about 550nm. Note how the left trough of the “W” and the peak of the “W” are near the maximum sensitivities of the M and L cones, respectively. The “W” shape occurs due to oxygenated hemoglobin in the skin, and having the M and L cone sensitivities fall where they do is what gives us the ability to read minute changes in skin color so easily.