Molecular Cytogenetics. Protocols and Applications by Yao-Shan Fan

By Yao-Shan Fan

Yao-Shan Fan and a panel of senior scientists and pioneering researchers describe in step by step type the major FISH ideas and people molecular applied sciences past FISH on hand for diagnostic prone in genetics and oncology. The tools comprise labeling FISH probes for DNA and RNA ambitions, fluorescence genotyping, CGH microarray, spectral karyotyping/multicolor FISH, and primed in situ labeling. There also are suggestions for multicolor fiber FISH, multi-telomere FISH, prenatal prognosis utilizing maternal blood, and preimplantation prognosis. Oncological tools comprise simultaneous fluorescence immunophenotyping and FISH for leukemia and lymphoma, HER2 amplification in breast melanoma, and CAC/PAC for melanoma cytogenetics.

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